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Minerals, hydrogen, alkaline, silicon, lithium, fluoride: what the trials say

Owner's question: what is not proven is not necessarily untrue. Each claim here is classified on a fixed scale (established, promising, plausible, contested, no signal, not reachable at home) with the trials behind it and a watch list of studies still to report. Nothing on this page is advice; a health benefit is never a reason we link to a product.

The sources

SourceWhat it found (quoted) and its limitsEvidence
Taylor KW, et al. Fluoride exposure and children's IQ scores: SR & MA. JAMA Pediatrics (2025) · new
Meta-analysis · n = 74 studies
each 1 mg/L urinary fluoride increase associated with lower IQ by "1.63 IQ points in children" (NIEHS summary); not enough data on 0.7 mg/L · Contested
Topic: fluoride; dose: Water/urinary fluoride
Limits: 52/74 studies high risk of bias; urinary vs water exposure
Evidence: strong
Free to read · source · added 2026-10-30
Zhou K, Shang Z, Yuan C, et al. Can molecular hydrogen supplementation enhance physical performance in healthy adults? SR & MA. Front Nutr 11:1387657 (2024) · new
Meta-analysis of RCTs · n = 597 (29 studies)
"These findings suggest that H2 supplementation is favorable in healthy adults to improve lower limb explosive power." · Promising (Narrow)
Topic: hydrogen_water; dose: Various H2 forms
Limits: Small effects; endurance and strength trivial
Evidence: strong
Free to read · source · added 2026-10-30
National Toxicology Program. NTP Monograph on the State of the Science Concerning Fluoride Exposure and Neurodevelopment and Cognition (NTP-MGRAPH-8) (2024) · new
Systematic review (hazard assessment) · n = n/a
moderate confidence that "higher levels of fluoride exposure ... are associated with lower IQ in children"; "insufficient data to determine if the low fluoride level of 0.7 mg/L" affects IQ · Contested (At 0.7 Mg/L)
Topic: fluoride; dose: Fluoride exposure >1.5 mg/L water
Limits: Most studies from high-exposure regions
Evidence: strong
Free to read · source · added 2026-10-30
Cochrane Oral Health. Water fluoridation for the prevention of dental caries (CD010856, 2024 update) (2024) · new
Systematic review · n = post-1975: 2908 children (dmft)
"The evidence suggests that water fluoridation may slightly reduce tooth decay in children."; post-1975 ~0.24 fewer decayed baby teeth per child (uncertain) · Established (Benefit Modest Today)
Topic: fluoride; dose: Community water fluoridation
Limits: Benefit smaller than pre-1975 era of no fluoride toothpaste; no adult studies
Evidence: strong
Free to read · source · added 2026-10-30
Zhou K, Liu M, Wang Y, et al. Effects of molecular hydrogen supplementation on fatigue and aerobic capacity in healthy adults: SR & MA. Front Nutr 10:1094767 (2023) · new
Meta-analysis · n = 402 (19 studies)
effects on RPE and lactate "small yet significant with low heterogeneity"; aerobic capacity "not significant and trivial" · Promising (Fatigue) / Negative (Aerobic Capacity)
Topic: hydrogen_water; dose: Various H2 forms (water, inhalation)
Limits: Small trials; mixed H2 delivery forms
Evidence: strong
Free to read · source · added 2026-10-30
Yoritaka A, et al. Randomized, double-blind, multicenter trial of hydrogen water for Parkinson's disease. Movement Disorders (2018) · new
RCT double-blind placebo, 14 centres · n = 178
"There were no significant differences (t-test; p > 0.05) in the total UPDRS score between the H2-water and placebo groups." (KAKEN final report) · Negative For Pd
Topic: hydrogen_water; dose: 1000 mL/day H2 water, 72 weeks
Limits: Dose possibly low; quote from grant report, not journal abstract
Evidence: strong
Paywalled · source · added 2026-10-30
Knudsen NN, Schullehner J, Hansen B, et al. Lithium in drinking water and incidence of suicide: nationwide individual-level cohort with 22 years follow-up. IJERPH 14(6):627 (2017) · new
Nationwide individual-level cohort (Denmark) · n = 3740113
"there does not seem to be a protective effect of exposure to lithium on the incidence of suicide" · Contested
Topic: lithium_water; dose: Li exposure (mean 11.6 ug/L; range below 31 ug/L)
Limits: Narrow exposure range
Evidence: strong
Free to read · source · added 2026-10-30
Gildengers A, et al. Low-dose lithium carbonate in mild cognitive impairment: 2-year pilot RCT. JAMA Neurology (PMID 41770546) (2026) · new
Pilot RCT placebo (safety/feasibility) · n = 80
No significant difference on any outcome; verbal memory "declined at about half the rate" (non-significant) [secondary report] · Uncertain (Pharmacologic)
Topic: lithium_water; dose: Lithium carbonate 150-300 mg/day (pharmacologic, not water)
Limits: Pill-dose far above water levels; 29/80 dropouts
Evidence: moderate
Access unknown · source · added 2026-10-30
Washington State Department of Health. Report of the Fluoride Science Review Panel (2025) · new
Agency review · n = n/a
"Community water fluoridation is an effective tool to prevent tooth decay."; "More research is needed on the potential neurodevelopmental risks" · Contested
Topic: fluoride; dose: CWF at 0.7 mg/L
Limits: Agency synthesis
Evidence: moderate
Free to read · source · added 2026-10-30
Li Y, Bing R, Liu M, et al. Can molecular hydrogen supplementation reduce exercise-induced oxidative stress in healthy adults? SR & MA. Front Nutr 11:1328705 (2024) · new
Meta-analysis · n = 76 (6 studies)
H2 can enhance antioxidant capacity "but not directly diminish the levels of exercise-induced oxidative stress" · Plausible
Topic: hydrogen_water; dose: Various H2 forms
Limits: Very small pooled n
Evidence: moderate
Free to read · source · added 2026-10-30
Jamialahmadi H, Khalili-Tanha G, Rezaei-Tavirani M, Nazari E. Effects of hydrogen-rich water on blood lipid profiles in metabolic disorders: SR & MA. Int J Endocrinol Metab 22(3):e148600 (2024) · new
Meta-analysis of double-blind RCTs · n = 357 (8 RCTs)
TG, TC and LDL "demonstrated slight decreases across the studies"; "further long-term trials involving larger populations are needed" · Promising (Weak)
Topic: hydrogen_water; dose: Hydrogen-rich water
Limits: Most pooled changes not significant
Evidence: moderate
Free to read · source · added 2026-10-30
Dhillon G, Buddhavarapu V, Grewal H, et al. Hydrogen water: extra healthy or a hoax? A systematic review. Int J Mol Sci 25(2):973 (2024) · new
Systematic review · n = 25 studies
"preliminary results in clinical trials and studies are encouraging"; "further research with larger sample sizes and rigorous methodologies is needed" [abstract only] · Promising
Topic: hydrogen_water; dose: Hydrogen-rich water
Limits: Heterogeneous small studies
Evidence: moderate
Free to read · source · added 2026-10-30
Albaker WI, Al-Hariri MT, et al. Beneficial effects of adding magnesium to desalinated drinking water on metabolic and insulin resistance parameters among patients with type 2 diabetes mellitus: an RCT. npj Clean Water 5:63 (2022) · new
RCT (3-arm, participant-blinded) · n = 230 randomized; 102 completed
Authors call findings an "initial indication" that Mg should be added to desalinated water; within-group HOMA-IR 2.9->2.5 at 50 mg/L · Promising
Topic: magnesium_water; dose: MgCl2 in desalinated water at 0, 20 or 50 mg/L; 1 L/day; 3 months (NCT04632277)
Limits: High dropout (102/230 completed); HbA1c between-group difference not significant (p=0.440); diet Mg not quantified
Evidence: moderate
Free to read · source · added 2026-10-30
Does much hyped alkaline electrolyzed water provide health benefits? A systematic review and narrative synthesis. Int J Environ Health Eng (ijehe.mui.ac.ir) (2022) · new
Systematic review · n = 9 studies
evidence "not sufficient enough for recommendation to the mass in general" · Unsupported (General Claims)
Topic: alkaline_water; dose: Alkaline electrolyzed water
Limits: Small heterogeneous studies
Evidence: moderate
Free to read · source · added 2026-10-30
Dupont C, Hébert G. Magnesium sulfate-rich natural mineral waters in the treatment of functional constipation - a review. Nutrients 12(7):2052 (2020) · new
Narrative review of 4 RCTs (industry-funded) · n = 4 RCTs, ~676 total
"magnesium sulfate-rich natural mineral waters may represent a natural treatment for FC" · Promising
Topic: sulfate_mg_constipation; dose: Hépar 1 L/d; Ensinger Schiller 1 L/d; Donat Mg 0.5 L/d
Limits: Funded by Nestlé Waters (Hépar owner); authors involved in Hépar trials
Evidence: moderate
Free to read · source · added 2026-10-30
LeBaron TW, Singh RB, Fatima G, et al. Effects of 24-week high-concentration hydrogen-rich water on body composition, blood lipid profiles and inflammation biomarkers in metabolic syndrome. Diabetes Metab Syndr Obes 13:889-896 (2020) · new
RCT double-blind placebo · n = 60
high-concentration HRW "significantly reduced blood cholesterol and glucose levels" · Promising
Topic: hydrogen_water; dose: H2-producing tablets, >5.5 mmol H2/day, 24 weeks
Limits: Partly funded by tablet maker; lead author industry fees; blood/breath H2 not measured
Evidence: moderate
Free to read · source · added 2026-10-30
Memon A, et al. Association between naturally occurring lithium in drinking water and suicide rates: SR & MA of ecological studies. Br J Psychiatry (2020) · new
Meta-analysis of ecological studies · n = 15 studies (9 pooled)
total suicide "pooled β = −0.27, 95% CI −0.47 to −0.08; P = 0.006, I2 = 83.3%"; studies "subject to the ecological fallacy/bias" · Contested
Topic: lithium_water; dose: Natural Li in water
Limits: Ecological; high heterogeneity; excludes individual-level null cohort
Evidence: moderate
Free to read · source · added 2026-10-30
Dupont C, et al. Time to treatment response of a magnesium- and sulphate-rich natural mineral water in functional constipation. Nutrition (PMID 31170680) (2019) · new
RCT double-blind placebo · n = 226
Responders 50% vs 29% at week 2 (p = 0.001) [figures as reported in Dupont & Hébert 2020 review; primary abstract not retrieved] · Promising
Topic: sulfate_mg_constipation; dose: Hépar 1 L/day
Limits: Industry-linked; short
Evidence: moderate
Paywalled · source · added 2026-10-30
Chycki J, et al. Alkaline water improves exercise-induced metabolic acidosis and enhances anaerobic exercise performance in combat sport athletes. PLoS One (2018) · new
RCT double-blind placebo · n = 16
"drinking alkalized water enhances hydration, improves acid-base balance and anaerobic exercise performance" · Promising (Narrow, Athletes)
Topic: alkaline_water; dose: Mineral-based highly alkaline water, 3 weeks
Limits: n=16; mineral content confounded with pH
Evidence: moderate
Free to read · source · added 2026-10-30
Schneider I, Greupner T, Hahn A. Magnesium bioavailability from mineral waters with different mineralization levels in comparison to bread and a supplement. Food & Nutrition Research 61 (2017) · new
Randomized crossover (bioavailability) · n = 22
Serum Mg AUC0-10h "revealed no significant differences among the treatment groups"; Mg-rich water called "a calorie-free magnesium source" · Established (As Mg Source / Bioavailability)
Topic: magnesium_water; dose: 100 mg Mg from 4 mineral waters, bread or supplement, single doses
Limits: Acute single-dose; surrogate endpoint only
Evidence: moderate
Free to read · source · added 2026-10-30
Dose-response relationship between dietary magnesium intake and cardiovascular mortality: systematic review and dose-based meta-regression of prospective studies. J Trace Elem Med Biol 38:64-73 (2016) · new
Meta-analysis of prospective cohorts (diet, not water) · n = 449748 (8 studies)
CVD mortality risk "reduced by 16% in women and 8% in men" (highest vs lowest intake); "No significant linear dose-response relationship was found" [abstract only] · Plausible (Water-Specific)
Topic: magnesium_water; dose: Dietary Mg intake (all sources)
Limits: Diet not water; observational; dose-response only in women/US
Evidence: moderate
Paywalled · source · added 2026-10-30
Naumann J, et al. Ensinger Schiller Quelle RCT (as reported in Dupont & Hébert 2020) (2016) · new
RCT double-blind placebo · n = 100
Bowel movements wk3 2.02 vs 0.88/week (p = 0.005); no significant effect at week 6 [as reported in review] · Promising
Topic: sulfate_mg_constipation; dose: 1 L/day (4x0.25 L) sulfate-rich water, 6 weeks
Limits: Effect not sustained at 6 weeks
Evidence: moderate
Free to read · source · added 2026-10-30
Weidman J, Holsworth RE Jr, Brossman B, et al. Effect of electrolyzed high-pH alkaline water on blood viscosity in healthy adults. JISSN 13:45 (2016) · new
RCT double-blind · n = 100
high-pH water "reduced high-shear viscosity by an average of 6.30% compared to 3.36%" (p = 0.03) · Unsupported For Clinical Hydration Benefit
Topic: alkaline_water; dose: Electrolyzed high-pH water vs purified water during recovery
Limits: Funded by Essentia; surrogate endpoint; osmolality/body mass no difference
Evidence: moderate
Free to read · source · added 2026-10-30
Bothe G, et al. Donat Mg RCT (as reported in Dupont & Hébert 2020) (2015) · new
RCT double-blind placebo · n = 106
Bowel movements wk6 6.62 vs 4.47 (p = 0.001) [as reported in review] · Promising
Topic: sulfate_mg_constipation; dose: Donat Mg 0.5 L/day, 6 weeks
Limits: Industry-linked; one arm stopped early
Evidence: moderate
Free to read · source · added 2026-10-30
Galetti V, Kujinga P, Mitchikpè CE, ... Zimmermann MB, Moretti D. Efficacy of highly bioavailable zinc from fortified water: an RCT in rural Beninese children. Am J Clin Nutr (NCT01790321) (2015) · new
RCT double-blind, 20 weeks · n = 277
"Consumption of filtered water fortified with a low dose of highly bioavailable zinc is an effective intervention"; "We detected no effect on diarrhea or growth" · Established In Deficient Children / Unsupported In Replete Adults
Topic: zinc_water; dose: Zinc-fortified filtered water delivering 2.8 mg Zn/day
Limits: Deficient population; biomarker endpoint
Evidence: moderate
Free to read · source · added 2026-10-30
Dupont C, et al. Hépar RCT (as reported in Dupont & Hébert 2020) (2014) · new
RCT double-blind placebo · n = 244
Responders 39.0% vs 24.3% at week 4 (p = 0.028) [figures as reported in review] · Promising
Topic: sulfate_mg_constipation; dose: Hépar 1 L/day vs 1.5 L low-mineral water
Limits: Industry-linked; 4 weeks; responder endpoint
Evidence: moderate
Free to read · source · added 2026-10-30
Wynn E, Krieg MA, Aeschlimann JM, Burckhardt P. Alkaline mineral water lowers bone resorption even in calcium sufficiency. Bone 44(1):120-4 (2009) · new
Randomized parallel (2 waters) · n = 30
"the alkaline water rich in bicarbonate led to a significant decrease of PTH and of S-CTX" [abstract only] · Promising
Topic: bicarbonate_calcium_water; dose: 1.5 L/day bicarbonate-rich alkaline water (PRAL -11.2) vs Ca-rich acidic water, 4 weeks
Limits: Small; 4 weeks; bone markers only, no BMD or fracture
Evidence: moderate
Paywalled · source · added 2026-10-30
Rylander R, Arnaud MJ. Mineral water intake reduces blood pressure among subjects with low urinary magnesium and calcium levels. BMC Public Health 4:56 (2004) · new
RCT (double-blind, 3 arms) · n = 70
"A significant decrease in blood pressure was found in the group consuming mineral water at 2 and 4 weeks" (effect reported among persons with initially low urinary Mg/Ca) [abstract only] · Promising
Topic: magnesium_water; dose: Low-mineral water vs Mg-enriched water vs natural mineral water, 4 weeks (Mg/Ca mg/L not captured)
Limits: Small; 4 weeks; effect in subgroup with low urinary Mg/Ca; doses not captured in this scan
Evidence: moderate
Free to read · source · added 2026-10-30
Foo LC, Zainab T, Goh SY, et al. Iodization of village water supply in the control of endemic iodine deficiency in rural Sarawak, Malaysia. Biomed Environ Sci 9(2-3):236-41 (1996) · new
Community intervention with control village · n = not captured
"goitre prevalences were reduced in all the villages (by 22.6% to 35.8%)" [abstract only] · Established In Deficient Settings / Not Relevant Where Salt Is Iodized
Topic: iodine_water; dose: Iodinated village water supply, 1 year
Limits: Old; non-randomized; deficient population only
Evidence: moderate
Paywalled · source · added 2026-10-30
Dubnov J, Eilon Y, Amster E, et al. Magnesium remineralization of desalinated drinking water and residents' health outcomes: a prospective cohort baseline study. Research Square preprint (under review BMC Public Health) (2026) · new
Prospective cohort - baseline (preprint, not peer reviewed) · n = 443
Baseline only; authors state findings do not establish causal effects · Plausible (Watch)
Topic: magnesium_water; dose: Planned Mg addition ~20-30 mg/L to desalinated supply from April 2026; follow-up 12 and 24 months
Limits: Preprint; self-report; no outcome data yet
Evidence: weak
Free to read · source · added 2026-10-30
Friedberg F, et al. Comparing different doses of hydrogen enriched water in a pilot randomized treatment trial in chronic fatigue syndrome (2026) · new
Pilot RCT single-blind, dose comparison (no placebo) · n = 50
"No significant outcome differences were observed between the two dosing conditions." [abstract only] · Uncertain
Topic: hydrogen_water; dose: 2-3 glasses/day vs escalation to 4-5 glasses/day, 16 weeks
Limits: No placebo arm; pilot
Evidence: weak
Access unknown · source · added 2026-10-30
Todorovic N, Baltic S, ... Ostojic SM. Effects of 8-week hydrogen-rich water on appetite, body composition, sleep and GLP-1 in obese adults (HYDRAPPET), NCT06722326. Preprints.org (2025) · new
RCT double-blind placebo (preprint, not peer reviewed) · n = 35-36
HRW "significantly mitigated cravings (P = 0.05)"; no between-group body composition difference · Promising (Unconfirmed)
Topic: hydrogen_water; dose: 1.0 L/day HRW (~15 mg H2), 8 weeks
Limits: Preprint; small; borderline p; co-author from H2 industry (Tarnava) per author list
Evidence: weak
Free to read · source · added 2026-10-30
Aron L, ... Yankner B. Lithium deficiency and the onset of Alzheimer's disease. Nature (2025) · new
Human post-mortem tissue + mouse experiments · n = dozens of brains + mice
Yankner: "Before recommending lithium orotate, we need to determine the effective and safe dose range in people." (NIH Research Matters) · Plausible (Mechanism)
Topic: lithium_water; dose: Lithium-depleted vs lithium orotate diets/water (mice)
Limits: Mechanistic/animal; no human trial yet
Evidence: weak
Paywalled · source · added 2026-10-30
Fraiha-Pegado J, de Paula VJR, Alotaibi T, Forlenza O, Hajek T. Trace lithium levels in drinking water and risk of dementia: a systematic review. Int J Bipolar Disord 12:32 (2024) · new
Systematic review · n = 5 studies
"trace-Li levels in the water are sufficient to lower the incidence or mortality from dementia" (authors' view; calls for trials) · Contested
Topic: lithium_water; dose: Trace Li in water
Limits: Only 5 observational studies; omits some nulls
Evidence: weak
Free to read · source · added 2026-10-30
Lu Y, Chen H. Deuterium-depleted water in cancer therapy: a systematic review of clinical and experimental trials. Nutrients 16(9):1397 (2024) · new
Systematic review (14 lab/animal + 1 RCT) · n = 15 studies; RCT n=44
authors call for "More extensive randomized controlled trials"; review acknowledges high risk of bias · Plausible (Weak)
Topic: deuterium_depleted_water; dose: DDW +/- chemotherapy
Limits: 1 small human RCT; mechanism unconfirmed
Evidence: weak
Free to read · source · added 2026-10-30
Duthie AC, Hannah J, Batty GD, et al. Low-level lithium in drinking water and subsequent risk of dementia: cohort study. Int J Geriatr Psychiatry e5890 (2023) · new
Retrospective cohort (Scottish Mental Survey 1932) · n = 37597
"Our results do not support an association between extremely low levels of lithium and later dementia risk." · Contested
Topic: lithium_water; dose: Mean water Li 1.45 ug/L
Limits: Very low exposure range
Evidence: weak
Free to read · source · added 2026-10-30
Shlezinger M, Amitai Y, Goldenberg I, Atar S, Shechter M. Acute myocardial infarction severity, complications, and mortality associated with lack of magnesium intake through consumption of desalinated seawater. Magnesium Research 32(2):39-50 (2019) · new
Observational (two-region comparison) · n = 380
"we found non significant higher MACE and 1-year mortality with the use of DSW" [abstract only] · Plausible
Topic: magnesium_water; dose: Residential water Mg 5.4 mg/L (desalinated) vs 25.1 mg/L
Limits: Ecological exposure; confounding; non-significant primary outcome
Evidence: weak
Paywalled · source · added 2026-10-30
Parker WF, Gorges RJ, Gao YN, et al. Association between groundwater lithium and the diagnosis of bipolar disorder and dementia in the United States. JAMA Psychiatry (research letter) (2018) · new
Ecological (claims data) · n = 4.2 million insured adults
apparent link "driven by unaccounted variation in demographics, health care resources, and diagnostic practices" [via Alzforum] · Contested
Topic: lithium_water; dose: Groundwater Li high (mean 141 ug/L) vs low (6 ug/L)
Limits: Ecological
Evidence: weak
Paywalled · source · added 2026-10-30
Zalvan CH, et al. Comparison of Mediterranean diet + alkaline water vs PPI for laryngopharyngeal reflux. JAMA Otolaryngol Head Neck Surg (2017) · new
Retrospective cohort (two time periods) · n = 184
RSI >=6-point reduction 62.6% vs 54.1% (difference not significant) [as reported by Healio] · Plausible
Topic: alkaline_water; dose: Plant-based Mediterranean diet + alkaline water pH>8 vs PPI
Limits: Diet and water inseparable; non-randomized; historical control
Evidence: weak
Paywalled · source · added 2026-10-30
Kessing LV, et al. Association of lithium in drinking water with the incidence of dementia. JAMA Psychiatry 74(10):1005-1010 (2017) · new
Nationwide nested case-control (Denmark) · n = 73731 cases; 733653 controls
IRR 0.83 (95% CI 0.81-0.85) for >15.0 ug/L but IRR 1.22 for 5.1-10.0 ug/L; "confounding from other factors associated with municipality of residence cannot be excluded" · Contested
Topic: lithium_water; dose: Municipal water Li >15.0 ug/L vs 2.0-5.0 ug/L
Limits: Non-linear; ecological exposure assignment
Evidence: weak
Free to read · source · added 2026-10-30
Davenward S, Bentham P, Wright J, Crome P, Job D, Polwart A, Exley C. Silicon-rich mineral water as a non-invasive test of the 'aluminum hypothesis' in Alzheimer's disease. J Alzheimers Dis 33(2):423-30 (2013) · new
Uncontrolled pilot (patients + carers) · n = ~15 AD + carers
"at least 3 out of 15 individuals" showed clinically relevant cognitive improvement; "a longer term study involving many more individuals is now warranted" [abstract only] · Plausible
Topic: silicon_water; dose: Up to 1 L/day Si-rich mineral water, 12 weeks
Limits: No placebo; tiny; Al hypothesis itself contested
Evidence: weak
Paywalled · source · added 2026-10-30
Advocate Health enews. Can bathing in vitamins boost your health? (quotes ACS chemist N. Langerman) (2013) · new
Expert commentary (secondary) · n = n/a
"there is absolutely no evidence that chlorine in water form is bad for your skin" (Langerman) · Unsupported (Health); Chemistry Of Dechlorination Plausible
Topic: vitamin_c_shower; dose: Vitamin C shower filters
Limits: No trials found in this scan
Evidence: weak
Free to read · source · added 2026-10-30
Koufman JA, Johnston N. Potential benefits of pH 8.8 alkaline drinking water as an adjunct in the treatment of reflux disease. Ann Otol Rhinol Laryngol 121(7):431-4 (2012) · new
In vitro · n = n/a
"The pH 8.8 alkaline water irreversibly inactivated human pepsin (in vitro)" [abstract only] · Plausible (Reflux Mechanism)
Topic: alkaline_water; dose: pH 8.8 water
Limits: No human outcome data
Evidence: weak
Paywalled · source · added 2026-10-30
Exley C, Korchazhkina O, Job D, et al. Non-invasive therapy to reduce the body burden of aluminium in Alzheimer's disease. J Alzheimers Dis 10(1):17-24 (2006) · new
Pre-post, no control · n = not captured
Urinary Al fell from 86.0 to 62.2 nmol/mmol creatinine; "Drinking the mineral water increased significantly (P<0.001) their urinary excretion of silicic acid" [abstract only] · Plausible
Topic: silicon_water; dose: 1.5 L/day silicic-acid-rich mineral water, 5 days
Limits: No control; 5 days; surrogate
Evidence: weak
Paywalled · source · added 2026-10-30
Directive 2009/54/EC on natural mineral waters, Annex III (permitted label indications) (2009) · new
Regulation · n = n/a
"Contains bicarbonate" >600 mg/l; "Contains calcium" >150 mg/l; "Contains magnesium" >50 mg/l; "May be laxative" - no criterion given · Regulatory Context
Topic: bicarbonate_calcium_water; dose: Label thresholds
Limits: Composition labels, not health-benefit evidence; EFSA nutrient claims (Reg. 1924/2006) not checked in this scan
Evidence: n/a
Free to read · source · added 2026-10-30

Evidence grade: strong = trials, large field studies or official datasets; moderate = smaller or lab studies with real water; weak = single small studies, makers' specs or secondary reports. "Free to read" means the source itself is free to read online.

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